The SARS-CoV-2 B.1.351 lineage (VOC β) is outgrowing the B.1.1.7 lineage (VOC α) in some French regions in April 2021

Author:

Roquebert Bénédicte1,Trombert-Paolantoni Sabine1,Haim-Boukobza Stéphanie1,Lecorche Emmanuel1,Verdurme Laura1,Foulongne Vincent2,Sofonea Mircea T.34,Alizon Samuel34ORCID

Affiliation:

1. Laboratoire Cerba, Saint Ouen L’Aumône, France

2. Laboratoire de Virologie, CHU de Montpellier, Montpellier, France

3. These authors contributed equally to this article.

4. MIVEGEC, CNRS, IRD, Université de Montpellier, Montpellier, France

Abstract

To assess SARS-CoV-2 variants spread, we analysed 36,590 variant-specific reverse-transcription-PCR tests performed on samples from 12 April–7 May 2021 in France. In this period, contrarily to January–March 2021, variants of concern (VOC) β (B.1.351 lineage) and/or γ (P.1 lineage) had a significant transmission advantage over VOC α (B.1.1.7 lineage) in Île-de-France (15.8%; 95% confidence interval (CI): 15.5–16.2) and Hauts-de-France (17.3%; 95% CI: 15.9–18.7) regions. This is consistent with VOC β’s immune evasion abilities and high proportions of prior-SARS-CoV-2-infected persons in these regions.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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