Affiliation:
1. Robert Koch Institute, Berlin, Germany
Abstract
The Delta variant has become the dominant strain of SARS-CoV-2. We summarised the evidence on COVID-19 vaccine effectiveness (VE) identified in 17 studies that investigated VE against different endpoints. Pooled VE was 63.1% (95% confidence interval (CI): 40.9–76.9) against asymptomatic infection, 75.7% (95% CI: 69.3–80.8) against symptomatic infection and 90.9% (95% CI: 84.5–94.7) against hospitalisation. Compared with the Alpha variant, VE against mild outcomes was reduced by 10–20%, but fully maintained against severe COVID-19.
Publisher
European Centre for Disease Control and Prevention (ECDC)
Subject
Virology,Public Health, Environmental and Occupational Health,Epidemiology
Reference20 articles.
1. World Health Organization (WHO). Weekly epidemiological update on COVID-19 - 14 September 2021. Edition 57. Geneva: WHO; 2021. Available from: https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---14-september-2021
2. Efficacy and effectiveness of COVID-19 vaccines against SARS-CoV-2 infection: interim results of a living systematic review, 1 January to 14 May 2021.;Harder;Euro Surveill,2021
3. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.;Sterne;BMJ,2016
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