Multidrug-resistant organisms in patients from Ukraine in the Netherlands, March to August 2022

Author:

Zwittink Romy D1ORCID,Wielders Cornelia CH1ORCID,Notermans Daan W1ORCID,Verkaik Nelianne J2ORCID,Schoffelen Annelot F1ORCID,Witteveen Sandra1ORCID,Ganesh Varisha A1,de Haan Angela1ORCID,Bos Jeroen1,Bakker Jacinta1ORCID,Schneeberger-van der Linden Caroline1,Kuijper Ed J1ORCID,de Greeff Sabine C1ORCID,Hendrickx Antoni PA1ORCID,

Affiliation:

1. Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands

2. SWAB Working Group Surveillance of Antibiotic Resistance, Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands

Abstract

Since March 2022, there has been an emergence of multidrug-resistant organisms (MDRO) in the Netherlands in patients originating from Ukraine (58 patients, 75 isolates). For about half of these patients, recent hospitalisation in Ukraine was reported. Genomic surveillance revealed that the majority of the MDRO represent globally spread epidemic lineages and that 60% contain New Delhi metallo-β-lactamase (NDM) genes. Professionals should be aware of an increase in such MDRO associated with migration and medical evacuation of people from Ukraine.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference16 articles.

1. de Greeff SC, Kolwijck E, Schoffelen AF, Verduin CM. NethMap 2022. Consumption of antimicrobial agents and antimicrobial resistance among medically important bacteria in the Netherlands in 2021 / MARAN 2022. Monitoring of Antimicrobial Resistance and Antibiotic Usage in Animals in the Netherlands in 2021. Bilthoven: Rijksinstituut voor Volksgezondheid en Milieu; 2022. Available from: https://www.rivm.nl/publicaties/nethmap-2022-consumption-of-antimicrobial-agents

2. Molecular characteristics of carbapenemase-producing Enterobacterales in the Netherlands; results of the 2014-2018 national laboratory surveillance.;van der Zwaluw;Clin Microbiol Infect,2020

3. World Health Organization Regional Office for Europe (WHO/Europe)/European Centre for Disease Prevention and Control (ECDC). Antimicrobial resistance surveillance in Europe 2022 – 2020 data. Copenhagen: WHO/Europe; 2022. Available from: https://apps.who.int/iris/handle/10665/351141. License: CC BY-NC-SA 3.0 IGO

4. Epidemiology of carbapenem-resistant and carbapenemase-producing Enterobacterales in the Netherlands 2017-2019.;Wielders;Antimicrob Resist Infect Control,2022

5. European Commission (EC). Ukraine: 1,000 Ukrainian patients transferred to European hospitals. Press release. Brussels: EC; 2022. Available from: https://ec.europa.eu/commission/presscorner/detail/en/IP_22_4882

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