Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022-Reference-Cited by-同舟云学术

Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022

Published:2022-07-14 Issue:28 Volume:27 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Peiró-Mestres Aida¹,Fuertes Irene²,Camprubí-Ferrer Daniel¹,Marcos María Ángeles³⁴¹,Vilella Anna⁵¹,Navarro Mireia⁴,Rodriguez-Elena Laura⁴,Riera Josep²,Català Alba²,Martínez Miguel J³⁴¹,Blanco Jose L⁶³,

Affiliation:

1. Barcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain

2. Dermatology Department, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain

3. Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain

4. Microbiology Department, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain

5. Preventive Medicine and Epidemiology Department, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain

6. Infectious Diseases Department, Hospital Clínic-IDIBAPS, Universitat de Barcelona, Barcelona, Spain

Abstract

A monkeypox (MPX) outbreak has expanded worldwide since May 2022. We tested 147 clinical samples collected at different time points from 12 patients by real-time PCR. MPX DNA was detected in saliva from all cases, sometimes with high viral loads. Other samples were frequently positive: rectal swab (11/12 cases), nasopharyngeal swab (10/12 cases), semen (7/9 cases), urine (9/12 cases) and faeces (8/12 cases). These results improve knowledge on virus shedding and the possible role of bodily fluids in disease transmission.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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