Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022

Author:

Antinori Andrea1ORCID,Mazzotta Valentina1ORCID,Vita Serena1,Carletti Fabrizio1,Tacconi Danilo2,Lapini Laura Emma2,D’Abramo Alessandra1,Cicalini Stefania1,Lapa Daniele1,Pittalis Silvia1,Puro Vincenzo1,Rivano Capparuccia Marco3,Giombini Emanuela1,Gruber Cesare Ernesto Maria1,Garbuglia Anna Rosa1,Marani Alessandra1,Vairo Francesco1,Girardi Enrico1,Vaia Francesco1,Nicastri Emanuele1,

Affiliation:

1. National Institute for Infectious Diseases ‘Lazzaro Spallanzani’ (IRCCS), Rome, Italy

2. Department of Specialised and Internal Medicine, Infectious Diseases Unit, San Donato Hospital, Arezzo, Italy

3. Infectious and Tropical Disease Unit, AOU Policlinico Umberto I, Rome, Italy

Abstract

Since May 2022, an outbreak of monkeypox has been ongoing in non-endemic countries. We report four cases in Italy in young adult men reporting condomless sexual intercourse. The patients are in good clinical condition with no need for specific antiviral drugs. Biological samples from seminal fluid were positive for monkeypox viral DNA. For many other viruses found in semen there is no evidence of sexual transmission. The possibility of sexual transmission of monkeypox virus needs to be investigated.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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