Whole genome sequencing and phylogenetic analysis of West Nile virus lineage 1 and lineage 2 from human cases of infection, Italy, August 2013-Reference-Cited by-同舟云学术

Whole genome sequencing and phylogenetic analysis of West Nile virus lineage 1 and lineage 2 from human cases of infection, Italy, August 2013

Published:2013-09-19 Issue:38 Volume:18 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Barzon L¹²,Pacenti M¹,Franchin E²¹,Lavezzo E²,Masi G²,Squarzon L²,Pagni S¹²,Toppo S²,Russo F³,Cattai M¹,Cusinato R¹,Palù G¹²

Affiliation:

1. Regional Reference Laboratory, Microbiology and Virology Unit, Padova University Hospital, Padova, Italy

2. Department of Molecular Medicine, University of Padova, Padova, Italy

3. Department of Public Health and Screening, Veneto Region, Venice, Italy

Abstract

A human outbreak of West Nile virus (WNV) infection caused by WNV lineage 2 is ongoing in northern Italy. Analysis of six WNV genome sequences obtained from clinical specimens demonstrated similarities with strains circulating in central Europe and Greece and the presence of unique amino acid changes that identify a new viral strain. In addition, WNV lineage 1 Livenza, responsible for a large outbreak in north-eastern Italy in 2012, was fully sequenced from a blood donor during this 2013 outbreak.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference31 articles.

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