Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation
Author:
Affiliation:
1. Institute of Physiological Chemistry, Philipps-University Marburg, Karl-von-Frisch-Strasse 1, 35033 Marburg, Germany
2. The Kekulé Institute for Organic Chemistry and Biochemistry, University of Bonn, 53121 Bonn, Germany
Abstract
Publisher
Portland Press Ltd.
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://portlandpress.com/biochemj/article-pdf/383/3/507/714602/bj3830507.pdf
Reference47 articles.
1. Differential membrane interactions of saposins A and C: implications for the functional specificity;Qi;J. Biol. Chem.,2001
2. Biosynthesis and degradation of mammalian glycosphingolipids;Sandhoff;Philos. Trans. R. Soc. Lond. B,2003
3. Saposin C is required for lipid presentation by human CD1b;Winau;Nature Immunol.,2004
4. The evolutionary history of prosaposin: two successive tandem-duplication events gave rise to the four saposin domains in vertebrates;Hazkani-Covo;J. Mol. Evol.,2002
5. Crystal structure of saposin B reveals a dimeric shell for lipid binding;Ahn;Proc. Natl. Acad. Sci. U.S.A.,2003
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