Cellular strategies to cope with protein aggregation-Reference-Cited by-同舟云学术

Cellular strategies to cope with protein aggregation

Published:2016-10-15 Issue:2 Volume:60 Page:153-161
ISSN:0071-1365
Container-title:Essays in Biochemistry
language:en
Short-container-title:

Author:

Scior Annika¹,Juenemann Katrin¹²,Kirstein Janine¹

Affiliation:

1. Leibniz-Institute for Molecular Pharmacology (FMP) im Forschungsverbunbd Berlin e.V., Robert-Roessle-Straße 10, 13125 Berlin, Germany

2. Academic Medical Center Amsterdam, Department of Cell Biology and Histology, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

Abstract

Nature has evolved several mechanisms to detoxify intracellular protein aggregates that arise upon proteotoxic challenges. These include the controlled deposition of misfolded proteins at distinct cellular sites, the protein disaggregation and refolding by molecular chaperones and/or degradation of misfolded and aggregated protein species by cellular clearance pathways. In this article, we discuss cellular the strategies of prokaroytes and eukaryotes to control protein aggregation.

Publisher

Portland Press Ltd.

Subject

Molecular Biology,Biochemistry

Link

https://portlandpress.com/essaysbiochem/article-pdf/60/2/153/481117/bse0600153.pdf

Reference43 articles.

1. Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation;Chui;Nat. Med.,1999

2. Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation;Kumar-Singh;Neurobiol. Dis.,2000

3. Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models;Cheng;J. Biol. Chem.,2007

4. Opposing activities protect against age-onset proteotoxicity;Cohen;Science,2006

5. Reduced IGF-1 signaling delays age-associated proteotoxicity in mice;Cohen;Cell,2009

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