Extracellular vesicles: translational challenges and opportunities-Reference-Cited by-同舟云学术

Extracellular vesicles: translational challenges and opportunities

Published:2018-09-21 Issue:5 Volume:46 Page:1073-1082
ISSN:0300-5127
Container-title:Biochemical Society Transactions
language:en
Short-container-title:

Author:

Clemmens Hannah¹,Lambert Daniel W.¹²^ORCID

Affiliation:

1. Academic Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, S10 2TA Sheffield, U.K.

2. Sheffield Institute for Nucleic Acids, University of Sheffield, S10 2TA Sheffield, U.K.

Abstract

Extracellular vesicles (EVs) are a heterogeneous group of small lipid-enclosed structures with myriad roles in physiology and disease. The recent surge of interest in EVs has led to greater understanding of their biology and appreciation of how they might be utilised as diagnostic and therapeutic tools. There remain, however, a number of challenges that must be overcome before EVs may be used routinely in the clinic. In this review we will discuss the translational potential of EVs and the current technologies available to isolate, purify and analyse EVs and their contents.

Publisher

Portland Press Ltd.

Subject

Biochemistry

Link

https://portlandpress.com/biochemsoctrans/article-pdf/46/5/1073/479386/bst-2018-0112c.pdf

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