Affiliation:
1. Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, U.K.
Abstract
Systems biology describes the collection of a set of measurements on a system, integrated with a mathematical model of that system. The model and the measurements must be made together and refined iteratively, requiring close collaboration between biologists and modellers. A complete cell is probably too large and complicated to model yet, but simplified subsystems will probably produce valuable results. I consider various ways of simplifying the system and conclude that the biggest challenge is to get everyone working together productively.
Cited by
9 articles.
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