Screening for tuberculosis infection in children and adolescents in Russia – past, present, future

Author:

Аksenova V. A.1,Baryshnikova L. A.2,Klevno N. I.1,Kudlay D. A.3

Affiliation:

1. National Medical Research Center of Phthisiopulmonology and Infectious Diseases; I. M. Sechenov First Moscow State Medical University (Sechenov University)

2. N. V. Postnikov Samara Regional Clinical TB Dispensary

3. Immunology Research Institute by the Russian Federal Medical Biological Agency

Abstract

The article presents a brief overview of the establishment and development of screening system in the pediatric population for tuberculosis and latent tuberculosis infection - from Koch alt-tuberculin to modern recombinant tuberculosis allergens for intradermal administration and in vitro laboratory tests. It gives extensive data on clinical research and the introduction into practical public health of the Russian Federation of the test with recombinant tuberculosis allergen as a screening method for tuberculosis in children from 8 to 14 years old inclusively.

Publisher

New Terra

Subject

General Medicine

Reference78 articles.

1. Аksenova V.А., Baryshnikova L.А., Klevno N.I. et al. Topical issues of mass screening in children for tuberculosis under current conditions. Nauchno-Prakticheskiy Retsenziruemy Journal Doktor.ru, 2012, no. 8 (76), pp. 27-29. (In Russ.)

2. Аksenova V.А., Baryshnikova L.А., Klevno N.I. Skriningovoe obsledovanie detey i podrostkov s tselyu vyyavleniya tuberkuleznoy infektsii. Metod. rukovodstvo. [Mass screening in children and adolescents aimed to detect tuberculous infection. Guidelines]. Moscow, 2018, 47 p.

3. Аksenova V.А., Baryshnikova L.А., Klevno N.I. Current approaches to screening of tuberculous infection in children and adolescents in Russia. Med. Soviet, 2015, no. 4, pp. 30-35. (In Russ.)

4. Аksenova V.А., Baryshnikova L.А., Klevno N.I., Sokolskaya E.А., Dolzhenko E.N., Shuster A.M., Martyanov V.А., Kudlay D.А., Nikolenko N. Yu., Kurilla А.А. New opportunities for screening and diagnostics of various manifestations of tuberculous infection in children and adolescents in Russia. Voprosy Sovremennoy Pediatrii, 2011, no. 4, pp. 16-22. (In Russ.)

5. Аksenova V.А., Klevno N.I., Baryshnikova L.А., Kudlay D.А., Nikolenko N. Yu., Kurilla А.А. Vyavleniye tuberkuleza i taktika dispansernogo nabludeniya za litsami iz grupp riska s ispolzovaniyem rekombinantnogo tuberkuleznogo allergena - Diaskintest®. Metod. ukazaniya. [Detection of tuberculosis and tactics for dispensary follow-up over risk groups with the use of the recombinant tuberculous allergen - Diaskintest®. Guidelines]. Moscow, 2011, 19 p.

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