Incidence of Precipitated Withdrawal During a Multisite Emergency Department–Initiated Buprenorphine Clinical Trial in the Era of Fentanyl-Reference-Cited by-同舟云学术

Incidence of Precipitated Withdrawal During a Multisite Emergency Department–Initiated Buprenorphine Clinical Trial in the Era of Fentanyl

Published:2023-03-30 Issue:3 Volume:6 Page:e236108
ISSN:2574-3805
Container-title:JAMA Network Open
language:en
Short-container-title:JAMA Netw Open

Author:

D’Onofrio Gail¹²³,Hawk Kathryn F.¹³,Perrone Jeanmarie⁴,Walsh Sharon L.⁵,Lofwall Michelle R.⁵,Fiellin David A.¹²³,Herring Andrew⁶

Affiliation:

1. Department of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut

2. Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut

3. School of Public Health, Yale School of Medicine, New Haven, Connecticut

4. Department of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia

5. Center on Drug and Alcohol Research, University of Kentucky College of Medicine, Lexington

6. Department of Emergency Medicine, Highland Hospital Oakland, Oakland, California

Abstract

This cohort study examines the incidence of precipitated withdrawal comparing traditional sublingual buprenorphine with a 7-day extended-release injectable initiated in the emergency department (ED).

Publisher

American Medical Association (AMA)

Subject

General Medicine

Link

https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2802898/donofrio_2023_ld_230039_1679406284.87758.pdf

Reference6 articles.

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2. Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial.;D’Onofrio;JAMA,2015

3. Buprenorphine initiation strategies for opioid use disorder and pain management: a systematic review.;Spreen;Pharmacotherapy,2022

4. The design and conduct of a randomized clinical trial comparing emergency department initiation of sublingual versus a 7-day extended-release injection formulation of buprenorphine for opioid use disorder: Project ED Innovation.;D’Onofrio;Contemp Clin Trials,2021

5. Sublingual buprenorphine/naloxone precipitated withdrawal in subjects maintained on 100mg of daily methadone.;Rosado;Drug Alcohol Depend,2007

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