High Interindividual Variability of Methadone Enantiomer Blood Levels to Dose Ratios
Author:
Affiliation:
1. Département Universitaire de Psychiatrie Adulte, Unité de Biochimie et Psychopharmacologie Clinique, CH-1008 Prilly-Lausanne, Switzerland
2. Essen, Germany
Publisher
American Medical Association (AMA)
Subject
Psychiatry and Mental health,Arts and Humanities (miscellaneous)
Link
http:///jamapsychiatry/article-pdf/55/1/89/17310702/ylt0198-4-1.pdf
Reference10 articles.
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3. Replacement of (R)-methadone by a double dose of (R,S)-methadone in addict patients: interindividual variability of the (R)/(S) ratios and evidence of adaptive changes in methadone pharmacokinetics.;Eap;Eur J Pharmacol,1996
4. Fluvoxamine and fluoxetine do not interact in the same way with the metabolism of the enantiomers of methadone.;Eap;J Clin Psychopharmacol,1997
5. Ultrarapid hydroxylation of debrisoquine in a Swedish population: analysis of the molecular genetic basis.;Dahl;J Pharmacol Exp Ther,1995
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