Some controversies related to questionable clinical uses of methadone for chronic non-cancer pain and in palliative care
Author:
Affiliation:
1. Academic Hospital , Uppsala , Sweden
Publisher
Walter de Gruyter GmbH
Subject
Anesthesiology and Pain Medicine,Neurology (clinical)
Link
https://www.degruyter.com/document/doi/10.1515/sjpain-2020-0178/pdf
Reference25 articles.
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2. Melichar, JK, Hume, SP, Williams, TM, Daglish, Taylor, LG, Ahmed, R, et al.. Using [11C] diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: clinical and preclinical studies. J Pharmacol Exp Therapeut 2005;312:309–15. https://doi.org/10.1124/jpet.104.072686.
3. Lingford-Hughes, A. Human brain imaging and substance abuse. Curr Opin Pharmacol 2005;5:42–6. https://doi.org/10.1016/j.coph.2004.10.002.
4. Hume, SP, Lingford-Hughes, AR, Hataf, V, Hirani, A, Ahmed, R, Davies, A, et al.. Low sensitivity of the positron emission tomography ligand [11C]diprenorphine to agonist opioids. J Pharmacol Exp Therapeut 2007;322:661–7. https://doi.org/10.1124/jpet.107.121749.
5. Kling, MA, Carson, RE, Borg, L, Zametkin, A, Matochik, JA, Schluger, J, et al.. Opioid receptor imaging with positron emission tomography and [18F]cyclofoxy in long-term, methadone-treated former heroin addicts. J Pharmacol Exp Therapeut 2000;295:1070–6.
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