Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia
Author:
, Russell Lene1, Uhre Kis Rønn1, Lindgaard Ann Louise Syraach1, Degn Jette Fredlund1, Wetterslev Mik1, Sivapalan Praleene1, Anthon Carl Thomas1, Mikkelsen Vibe Sommer1, la Porta Louise Colette1, Jensen Thomas Steen1, Levin Charlotte Kastberg1, Kronborg Gitte1, Krogh-Madsen Rikke1, Plovsing Ronni Thermann Reitz1, Brix Helene1, Schønemann-Lund Martin1, Valbjørn Lone1, Lauritzen Sanne1, Koch Ellen Bjerre1, Sørensen Valdemar Oskar Ingemann1, Seitz-Rasmussen Hans Eric Sebastian1, Bestle Frederik Heiberg1, Andersen-Ranberg Nina Christine1, Mortensen Camilla Bekker1, Derby Cecilie Bauer1, Stormholt Emma Ritsmer1, Cao Yifei1, Strøm Thomas Steen1, Lærkner Eva1, Gilberg Christine1, Poulsen Michella1, Olsen Hanne Tanghus1, Rosenkilde Charlotte1, Haberlandt Trine1, Andersen Lars Peter Kloster1, Jensen Diana Bertelsen1, Hansen Mia Charlotte Krogh1, Aagaard Søren Rosborg1, Vestergaard Stine Rom1, Bunzel Anne-Marie Gellert1, Siegumfeldt Rine Moulvad1, Klitgaard Thomas Lass1, Krejberg Kirsten Uldal1, Nielsen Henrik1, Elvira Evangeline1, Kumari Hilda Nirmala1, Swaminathan Jayanthi1, Chander K Arun1, Rajan N Ganesh1, Thomas Sona1, Thomas Ann1, Odankadummai Vishnu1, Antony Anu M1, Kulkarni Atul P1, Baliga Nishanth1, Lodh Nirmalyo1, Vijayakumaran Swapna C1, Kalvit Kushal1, Sahu Tarun1, Patil Vijaya P1, Kothekar Amol T1, Bhosale Shilpushp J1, Gorade Manoj1, Shrivastava Anjana M1, Uddhavrao Jare Jagannath1, Sharma Ritika1, Mali Jyotsna1, Niranjan H R1, Lobo Celine1, Neve Vaishali1, Maurya Deepika1, Salunke Mahesh1, Pattanaik Santiswaroop1, Agrawal Akhliesh1, Hegde Ashit1, Badgurjar Rishi Kumar1, Jhaveri Binit N1, Sarje Digamber B1, Ananda H.J1, Sen Bitan1, Ambily C.M1, Jose Emilin P1, Kadam Vaijayanti1, Chiluka Annapurna1, Kuril Rohit1, Mathew Elizabeth1, Shirsekar Survana1, Kansal Sudha1, Dahiya Rinku1, Thakur Vijaya Kumar1, Tewatia Rajni1, Rawat Savita1, Tyagi Harsh1, Bhakare Meenakshi1, Bhise Chinmayee1, Girme Amit1, Kunjumon Lini T1, Jose Merlin1, Sharma Nikunj1, Bali Amol1, Patel Mayr1, Bhutaka Nirankar1, Pathrose Edwin1, Goyal Gopal1, Baby Riya1, Fernandez Roshini1, Bhattacharya Pradip K1, Kindo Srishti1, Aaditya A.1, Raj Kritiaka1, Poddar Aastha1, Ansari Aftab1, Alam Mustaque1, Khandagale Vijay1, Sarode Satish1, Garde Sanesh1, Shinde Sushant1, Jagtap Narndev1, Khartode Chagan1, Palange Amit1, Pawar Aishwarya1, Mulay Mayuri1, Pirzade Simrah1, Jagtap Mohini1, Rathod Balbhim1, Tanna Dhara1, Chaudhary Kinjal1, Deshpande Shubhangi1, Raj Rikin1, Ambapkar Sourab1, Ambapkar Shobhana1, Penurkar Mukund1, Sambare Amit1, Joshi Ravindra1, Kinolkar Bhushan1, Shaikh Tarannum Aslam1, Didriksson Helen1, Jönsson Carina1, Gagnö Gunilla1, Zacharias David1, Jong Margaret Lynn1, Roth Marianne1, Mader Rachelle1, Fazlija Laureta1, Akaltan Manuela1, Eichenberger Anjana1, Rüegg Gion1, Dill Tatjana1, Schoenmaekers Bruno1, Kumar Ashwani1, Rajbhandari Dorrilyn1, Arfin Sumaiya1, Bathla Nikita1, Joshi Rajesh1, Kunigari Mallikarjuna1, Munch Marie W.2, Myatra Sheila N.3, Vijayaraghavan Bharath Kumar Tirupakuzhi4, Saseedharan Sanjith5, Benfield Thomas6, Wahlin Rebecka R.7, Rasmussen Bodil S.8, Andreasen Anne Sofie9, Poulsen Lone M.10, Cioccari Luca11, Khan Mohd S.12, Kapadia Farhad13, Divatia Jigeeshu V.3, Brøchner Anne C.14, Bestle Morten H.15, Helleberg Marie16, Michelsen Jens17, Padmanaban Ajay4, Bose Neeta18, Møller Anders19, Borawake Kapil20, Kristiansen Klaus T.21, Shukla Urvi22, Chew Michelle S.23, Dixit Subhal24, Ulrik Charlotte S.25, Amin Pravin R.26, Chawla Rajesh27, Wamberg Christian A.28, Shah Mehul S.29, Darfelt Iben S.30, Jørgensen Vibeke L.31, Smitt Margit32, Granholm Anders2, Kjær Maj-Brit N.2, Møller Morten H.2, Meyhoff Tine S.2, Vesterlund Gitte K.2, Hammond Naomi E.3334, Micallef Sharon33, Bassi Abhinav35, John Oommen3536, Jha Anubhuti35, Cronhjort Maria7, Jakob Stephan M.11, Gluud Christian3738, Lange Theis39, Kadam Vaijayanti5, Marcussen Klaus V.19, Hollenberg Jacob7, Hedman Anders7, Nielsen Henrik8, Schjørring Olav L.8, Jensen Marie Q.2, Leistner Jens W.2, Jonassen Trine B.2, Kristensen Camilla M.2, Clapp Esben C.2, Hjortsø Carl J. S.2, Jensen Thomas S.2, Halstad Liv S.2, Bak Emilie R. B.2, Zaabalawi Reem2, Metcalf-Clausen Matias2, Abdi Suhayb2, Hatley Emma V.2, Aksnes Tobias S.2, Gleipner-Andersen Emil2, Alarcón Arif F.7, Yamin Gabriel7, Heymowski Adam7, Berggren Anton7, La Cour Kirstine10, Weihe Sarah10, Pind Alison H.10, Engstrøm Janus37, Jha Vivekanand33353640, Venkatesh Balasubramanian3341, Perner Anders233
Affiliation:
1. The COVID STEROID 2 Trial Group 2. Department of Intensive Care, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark 3. Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India 4. Apollo Hospitals, Chennai, India 5. SL Raheja Hospital, Mumbai, India 6. Department of Infectious Diseases, Copenhagen University Hospital–Amager and Hvidovre, Hvidovre, Denmark 7. Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden 8. Aalborg University Hospital, Aalborg University, Aalborg, Denmark 9. Department of Anaesthesia and Intensive Care, Copenhagen University Hospital, Herlev-Gentofte Hospital, Herlev, Denmark 10. Department of Anaesthesia and Intensive Care, Zealand University Hospital, Koege, Denmark 11. Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland 12. Rajendra Institute of Medical Sciences, Ranchi, India 13. Hinduja Hospital, Mahim, Mumbai, India 14. Department of Anaesthesia and Intensive Care, Kolding Hospital, Kolding, Denmark 15. Department of Anaesthesia and Intensive Care, Copenhagen University Hospital, North Zealand, Hilleroed, Denmark 16. Department of Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark 17. Department of Anaesthesia and Intensive Care, Odense University Hospital, Odense, Denmark 18. Gotri General Hospital, Gujarat, India 19. Department of Anaesthesia and Intensive Care, Slagelse Hospital, Slagelse, Denmark 20. Vishwaraj Hospital, Pune, India 21. Department of Anaesthesia and Intensive Care, Copenhagen University Hospital–Amager and Hvidovre, Hvidovre, Denmark 22. Symbiosis University Hospital and Research Centre, Lavale, India 23. Department of Anaesthesia and Intensive Care Medicine, Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden 24. Sanjeevan Hospital, Pune, India 25. Department of Respiratory Diseases, Copenhagen University Hospital–Amager and Hvidovre, Hvidovre, Denmark 26. Bombay Hospital Institute of Medical Sciences, Mumbai, India 27. Indraprastha Apollo Hospital, New Delhi, India 28. Department of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark 29. Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, India 30. Department of Anaesthesia and Intensive Care, Herning Hospital, Herning, Denmark 31. Department of Thoracic Anaesthesia, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark 32. Department of Neurointensive Care, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark 33. The George Institute for Global Health, University of New South Wales, Sydney, Australia 34. Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, Sydney, Australia 35. The George Institute for Global Health, New Delhi, India 36. Prasanna School of Public Health, Manipal Academy of Medical Sciences, Manipal, India 37. Copenhagen Trial Unit, Centre for Clinical Intervention Research, Capital Region, Copenhagen University Hospital, Rigshospitalet, Denmark 38. Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense 39. Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark 40. School of Public Health, Imperial College, London, England 41. Department of Intensive Care, Wesley Hospital, Brisbane, Australia
Publisher
American Medical Association (AMA)
Cited by
207 articles.
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