Effect of Treating Hyperphosphatemia With Lanthanum Carbonate vs Calcium Carbonate on Cardiovascular Events in Patients With Chronic Kidney Disease Undergoing Hemodialysis
Author:
Ogata Hiroaki1, Fukagawa Masafumi2, Hirakata Hideki3, Kagimura Tatsuo4, Fukushima Masanori4, Akizawa Tadao5, Suzuki Masashi6, Nishizawa Yoshiki6, Yamazaki Chikao6, Tanaka Shiro6, Kobayashi Shuzo6, Komuro Issei6, Tsuruya Kazuhiko6, Fujii Hideki6, Komaba Hirotaka6, Taniguchi Masatomo6, Hasegawa Takeshi6, Hamano Takayuki6, Mizobuchi Masahide6, Akiba Takashi6, Ando Ryoichi6, Iseki Kunitoshi6, Inaba Masaaki6, Kakuta Takatoshi6, Kato Hitoshi6, Kawanishi Hideki6, Kinugasa Eriko6, Koiwa Fumihiko6, Shigematsu Takashi6, Shoji Tetsuo6, Tsubakihara Yoshiharu6, Tominaga Yoshihiro6, Nakayama Masaaki6, Narita Ichiei6, Nishi Shinichi6, Nitta Kosaku6, Minakuchi Jun6, Yokoyama Keitaro6, Watanabe Yuzo6, Itami Noritomo6, Komota Tetsuo6, Yuasa Kenji6, Uehata Akimi6, Takahashi Ikuo6, Fujishima Mikihiko6, Kukita Kazutaka6, Yajima Ibuki6, Shishido Kanji6, Toshima Noriko6, Oroku Masato6, Yonaha Tomoki6, Goto Koshi6, Maeno Kazuyuki6, Tanaka Motoko6, Okuda Tomoko6, Tamura Hiroyuki6, Sawada Tokihiko6, Okuno Senji6, Fukushima Masaki6, Sekiguchi Takashi6, Nakamura Kazuyoshi6, Suzuki Ryuji6, Kowatari Teruo6, Masakane Ikuto6, Ito Minoru6, Hashimoto Hirofumi6, Ogata Hiroaki6, Aoyagi Ryuji6, Hidaka Sumi6, Mizuguchi Jun6, Shinoda Toshio6, Tanaka Kenji6, Sawada Shohei6, Kawakami Takahiro6, Iyoda Masayuki6, Shindo Yuki6, Tanaka Yoshiko6, Otsuka Masakazu6, Watanabe Makoto6, Tsujimoto Yoshihiro6, Ohtsubo Yoshihiko6, Okada Shigeki6, Yokochi Akio6, Kobayashi Naoto6, Morikawa Tomoki6, Higashi Harumichi6, Asakura Hiroshi6, Mukai Masanori6, Kanai Hidetoshi6, Kitaoka Tateki6, Kobayashi Masaki6, Karasawa Ryo6, Sanai Toru6, Kuwahara Michio6, Shikuma Satomi6, Takahashi Keiko6, Tokoo Masuo6, Koga Shoji6, Hayami Yoko6, Michihata Tetsuro6, Fujii Zenzo6, Suto Yasushi6, Ogiu Kazunori6, Chida Yoshiko6, Takeda Tetsuro6, Takatori Yuji6, Uekihara Soichi6, Kono Keiji6, Kitamura Ken6, Yonekura Yuriko6, Okuyama Akira6, Hamazaki Naoki6, Iizumi Tatsuo6, Shigemoto Kenichiro6, Ikenaga Hideki6, Kawai Toru6, Saito Kenichi6, Minamisono Noriko6, Tominaga Masahiro6, Miyamoto Takashi6, Kobayashi Hideo6, Yamazaki Hajime6, Ishimatsu Takashi6, Matsuo Dai6, Ikeda Hirofumi6, Hori Kei6, Shinozaki Nobuaki6, Kurogi Norimitsu6, Ozawa Noriyuki6, Hatashita Shizuo6, Imada Akio6, Naruse Tomohiko6, Sasagawa Isoji6, Miyamoto Kanyu6, Yoshino Masabumi6, Shirahama Akihiko6, Shirahama Chihiro6, Sakata Katsufumi6, Kashiki Tatsuji6, Nakanishi Shohei6, Tomizawa Muneo6, Ueno Hideki6, Harada Kazuhiro6, Saiki Toyonori6, Kimura Keita6, Horii Yasuhiro6, Suzuki Kazuhiro6, Hamaguchi Naoki6, Nakamura Akira6, Kondo Morihiro6, Kin Seikon6, Sanma Shoji6, Tanaka Yoshinori6, Hasegawa Shin6, Fujimi Satoru6, Takehara Akira6, Yuasa Yasuko6, Shibuya Yuko6, Hayama Naoaki6, Nakashima Yasunori6, Teramura Tomoko6, Inada Yoshifumi6, Oyabu Yuji6, Ikeda Naofumi6, Kumagai Fumiaki6, Yoshida Tetsuhiko6, Nasu Takahito6, Watanabe Yutaka6, Kobayashi Naoyuki6, Kohara Masaki6, Tani Yoshihiro6, Fukami Kei6, Onozaki Akira6, Nakajima Yutaka6, Tamura Masahito6, Kumakawa Kenjiro6, Ikeda Kiyoshi6, Suzuki Jun6, Sanaka Tsutomu6, Onda Yoshikazu6, Kaizu Kazo6, Oikawa Futoshi6, Noto Hiromitsu6, Sato Takahiko6, Yamazaki Akihisa6, Oshiro Yoshiyuki6, Yamamoto Shuzo6, Ogawa Chie6, Nakayama Fumiyoshi6, Motomura Kenichi6, Tanaka Takao6, Hagiwara Ryoji6, Takahashi Kazuaki6, Suzuki Nobukazu6, Kobayashi Shinya6, Tomori Koji6, Shibagaki Keigo6, Kamata Tatsuhiko6, Ariyoshi Takashi6, Hyakutake Hiroyuki6, Matsui Suguru6, Takano Makoto6, Ito Kenji6, Murata Toshiaki6, Okamoto Hidekazu6, Ogihara Masahiko6, Terajima Hisashi6, Uchida Takashi6, Morita Sohei6, Nishioka Masato6, Nakamura Hironori6, Kanno Yutaka6, Fujisawa Kazuhiro6, Tachiki Yutaka6, Yasuda Mitsunori6, Yanagita Motoko6, Tomita Kimio6, Kanamori Naoaki6, Takano Hideki6, Takeda Fukuji6, Kaneko Masashi6, Inukai Yoshihisa6, Hirata Akifumi6, Kasuga Hirotake6, Watanabe Tatsuaki6, Miyai Hironobu6, Natori Kunihiko6, Sato Toshimitsu6, Takada Joji6, Suga Yasunori6, Miyatani Kazuo6, Iijima Keitaro6, Tanaka Tsutomu6, Nakada Teruhiro6, Sato Takashi6, Fukuchi Fumiko6, Hamasaki Yoshinobu6, Wada Yoshifumi6, Suzuki Nobuyuki6, Hashimoto Masami6, Kaburagi Noriko6, Suenaga Matsuhiko6, Nomura Tomohide6, Haba Toshihito6, Murakami Kazutaka6, Kitano Keizo6, Kono Keiichi6, Suzuki Tomio6, Deguchi Fusae6, Nonaka Tatsuya6, Ozawa Yuko6, Maeda Kenji6, Sugiyama Satoshi6, Konemori Gen6, Mizuno Masao6, Shimano Yasunobu6, Nabeshima Kunihiro6, Hiramatsu Sadahiko6, Iida Yoshiyasu6, Tsuruta Yoshinari6, Kawamura Naoto6, Kumagai Etsuko6, Tsuboi Masato6, Tsukada Wataru6, Nakamura Yoshihiro6, Miyasaka Makoto6, Kawamura Hironori6, Hiramatsu Takeyuki6, Uda Susumu6, Wakai Haruki6, Obi Yasue6, Imai Tetsuya6, Miyahara Shigeru6, Sato Kazuto6, Miura Shunji6, Sugimura Kazunobu6, Miyazaki Takashi6, Ueno Kiichiro6, Yoshimine Kazuhiro6, Hashimoto Tetsuya6, Yamazaki Satoru6, Kobayashi Hiroyuki6, Terashima Masuo6, Oguchi Tomomasa6, Mori Masahiro6, Kuse Manabu6, Chiba Tetsuo6, Taira Takayasu6, Futoo Yasuo6, Hamada Takayoshi6, Horie Masanobu6, Miura Kohei6, Nagai Tetsushi6, Muramatsu Takehiko6, Tozawa Shuhei6, Mukai Hiroya6, Kurosawa Kosei6, Takahashi Junko6, Matsuhashi Naoki6, Yajima Aiji6, Furukawa Takeshi6, Ishida Yuji6, Miyata Masahiro6, Miyata Yukihiko6, Ohtsuka Takako6, Hasegawa Makoto6, Tamai Hirofumi6, Yoshioka Tetsuro6, Shiozaki Hiroshi6, Takemura Toru6, Mori Takashi6, Aoyama Isao6, Sawasaki Takako6, Nakayama Daisuke6, Toyama Katsuhide6, Ito Sumiko6, Ichinose Mayuri6, Inoue Kyoko6, Kataoka Kazuyoshi6, Ako Shinji6, Nagamoto Akihiro6, Arii Tatsuro6, Masutani Kosuke6, Sasatomi Yoshie6, Tachibana Naoki6, Kawamoto Atsuhiko6, Kaneda Hideaki6, Kojima Shinsuke6, Matsuo Miyuki6, Yoshidomi Mikio6, Nakagawa Yoko6, Kohno Kenichi6, Uno Emiko6, Shinno Tomoko6, Nagai Yoji6, Kuronaka Kaori6, Nishimura Yoichiro6, Nakagawa Satoshi6, Maeda Mitsuru6, Nogi Hideki6, Nishi Masanori6,
Affiliation:
1. Division of Nephrology, Department of Internal Medicine, Showa University Northern Yokohama Hospital, Tsuzuki, Yokohama, Kanagawa, Japan 2. Division of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan 3. Fukuoka Renal Clinic, Chuo-ku, Fukuoka, Japan 4. The Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Chuo-ku, Kobe, Hyogo, Japan 5. Division of Nephrology, Department of Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan 6. for the LANDMARK Investigators and Committees
Publisher
American Medical Association (AMA)
Reference33 articles.
1. Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients.;Ganesh;J Am Soc Nephrol,2001 2. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis.;Block;J Am Soc Nephrol,2004 3. Hyperphosphatemia of chronic kidney disease.;Hruska;Kidney Int,2008 4. Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS).;Tentori;Am J Kidney Dis,2008 5. Serum phosphate as a risk factor for cardiovascular events in people with and without chronic kidney disease: a large community based cohort study.;McGovern;PLoS One,2013
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