Gene Therapy in Alzheimer Disease—It May Be Feasible, but Will It Be Beneficial?

Author:

Honig Lawrence S.123

Affiliation:

1. Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York

2. The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Herbert and Florence Irving Medical Center, New York, New York

3. GH Sergievsky Center, Columbia University Herbert and Florence Irving Medical Center, New York, New York

Publisher

American Medical Association (AMA)

Subject

Clinical Neurology

Reference13 articles.

1. Adeno-associated viral vector (serotype 2)–nerve growth factor for patients with Alzheimer disease: a randomized clinical trial;Rafii;JAMA Neurol

2. Alzheimer’s disease drug development pipeline: 2017.;Cummings;Alzheimers Dement (N Y),2017

3. Accelerating stem cell trials for Alzheimer’s disease.;Hunsberger;Lancet Neurol,2016

4. A phase 1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer’s disease.;Rafii;Alzheimers Dement,2014

5. Treatment of Alzheimer’s disease: current management and experimental therapeutics.;Honig;Curr Transl Geriatr Exp Gerontol Rep,2013

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