Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease

Author:

Raghavan Neha S.1234,Dumitrescu Logan56,Mormino Elizabeth7,Mahoney Emily R.56,Lee Annie J.123,Gao Yizhe123,Bilgel Murat8,Goldstein David123,Harrison Theresa9,Engelman Corinne D.10,Saykin Andrew J.1112,Whelan Christopher D.13,Liu Jimmy Z.13,Jagust William9,Albert Marilyn14,Johnson Sterling C.15,Yang Hyun-Sik1617,Johnson Keith1617,Aisen Paul18,Resnick Susan M.8,Sperling Reisa1617,De Jager Philip L.1231920,Schneider Julie21,Bennett David A.21,Schrag Matthew5,Vardarajan Badri1234,Hohman Timothy J.56,Mayeux Richard1234,

Affiliation:

1. Department of Neurology, Columbia University Medical Center, New York, New York

2. Department of Neurology, The New York Presbyterian Hospital, New York

3. Taub Institute for Research on Alzheimer’s Disease and The Aging Brain, Columbia University Medical Center, New York, New York

4. The Institute for Genomic Medicine, Columbia University Medical Center, New York, New York

5. Vanderbilt Memory and Alzheimer’s Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee

6. Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee

7. Department of Neurology and Neurological Sciences, Stanford University, Stanford, California

8. Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, Maryland

9. Helen Wills Neuroscience Institute, University of California, Berkeley

10. Department of Population Health Sciences, University of Wisconsin, School of Medicine and Public Health, Madison

11. Department of Radiology and Imaging Sciences, Center for Neuroimaging, School of Medicine, Indiana University, Indianapolis

12. Department of Medical and Molecular Genetics, School of Medicine, Indiana University, Indianapolis

13. Research and Early Development, Biogen Inc, Cambridge, Massachusetts

14. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland

15. Alzheimer’s Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison

16. Department of Neurology, Massachusetts General Hospital, Boston

17. Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women’s Hospital, Boston, Massachusetts

18. Alzheimer’s Therapeutic Research Institute, Keck School of Medicine, University of Southern California, San Diego

19. Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, New York

20. Cell Circuits Program, Broad Institute, Cambridge, Massachusetts

21. Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois

Publisher

American Medical Association (AMA)

Subject

Clinical Neurology

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