Pharmacogenetics of antiviral agents for the treatment of COVID-19-Reference-Cited by-同舟云学术

Pharmacogenetics of antiviral agents for the treatment of COVID-19

Published:2022-01-07 Issue:1 Volume: Page:38-41
ISSN:2588-0527
Container-title:Pharmacogenetics and Pharmacogenomics
language:
Short-container-title:Fgen_Fgenom

Author:

Temirbulatov I. I.¹^ORCID,Kryukov A. V.¹^ORCID,Sychev D. A.¹^ORCID

Affiliation:

1. Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia

Abstract

Presented a literature review on the possible influence of pharmacogenetic markers on the efficacy and safety of COVID-19 therapy. Clinical studies of remdesivir and favipiravir are reviewed. Potential pharmacogenetic markers are described based on the available data on the pharmacokinetics of the drugs. We separately described the effect of the infectious-inflammatory process on the expression of cytochrome family enzymes.

Publisher

Publishing House OKI

Subject

General Medicine

Reference32 articles.

1. Agostini ML, Andres EL, Sims AC, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. mBio. 2018;9(2):e00221-18. DOI:10.1128/mBio.00221-18.

2. Siegel D, Hui HC, Doerffler E, et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. J Med Chem. 2017;60(5):1648–1661. DOI:10.1021/acs.jmedchem.6b01594.

3. Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020;30(3):269–271. DOI:10.1038/s41422-020-0282-0.

4. Beigel JH, Tomashek KM, Dodd LE, et al. Remdesivir for the Treatment of Covid-19 - Final Report. N Engl J Med. 2020;383(19):1813–1826. DOI:10.1056/NEJMoa2007764.

5. Consortium WHOST, Pan H, Peto R, et al. Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results. N Engl J Med. 2021;384(6):497–511. DOI:10.1056/NEJMoa2023184.

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metabolic support of antiviral therapy in patients with COVID-19;Experimental and Clinical Gastroenterology;2022-10-05