Rapid analysis of the effect of aminoglycosides on bacteria by using a sensor system based on a piezoelectric resonator with a lateral electric field-Reference-Cited by-同舟云学术

Rapid analysis of the effect of aminoglycosides on bacteria by using a sensor system based on a piezoelectric resonator with a lateral electric field

Published:2023-04-29 Issue:1-2 Volume:68 Page:4-10
ISSN:0235-2990
Container-title:Antibiotics and Chemotherapy
language:
Short-container-title:A&Ch

Author:

Guliy О. I.¹,Zaitsev B. D.²,Alsowaidi A. К. М.³,Karavaeva О. А.⁴,Semyonov A. P.⁵,Borodina I. A.⁵

Affiliation:

1. Institute of Biochemistry and Physiology of Plants and Microorganisms of the Russian Academy of Sciences – Subdivision of the Federal State Budgetary Research Institution Saratov Federal Scientific Centre of the Russian Academy of Sciences (IBPPM RAS)

2. Saratov Branch of the Kotelnikov Institute of Radio Engineering and Electronics, Russian Academy of Sciences, Saratov Branch

3. Saratov State University

4. Institute of Biochemistry and Physiology of Plants and Microorganisms of the Russian Academy of Sciences — Subdivision of the Federal State Budgetary Research Institution Saratov Federal Scientific Centre of the Russian Academy of Sciences (IBPPM RAS)

5. Saratov Branch of the Kotelnikov Institute of Radio Engineering and Electronics, Russian Academy of Sciences, Saratov Branch

Abstract

The possibility of express analysis of the effect of aminoglycoside antibiotics on bacteria (Escherichia coli) using a sensor system based on a piezoelectric resonator with a lateral electric field with an operating frequency range of 6–7 MHz is shown. E.coli strains, both sensitive and resistant to kanamycin were used for the experiments. During evaluating the kanamycin effect on bacteria, the change in the electrical impedance modulus of the resonator was used as an analitical signal. It has been established that the criterion for the antibiotic bacteria sensitivity is the change in the modulus of the sensor electrical impedance after antibiotic exposure on bacteria at any frequency near the resonance. The sensor is highly sensitive and allows diagnosing the antimicrobial susceptibility of bacteria within 7–9 minutes.

Publisher

Publishing House OKI

Subject

Infectious Diseases,Microbiology (medical),General Medicine,Microbiology

Reference21 articles.

1. Internet-resurs http://www.un.org/apps/news/story.asp?NewsID=47691#.VmZ00ImLR5w

2. Leung E., Weil D.E., Raviglione M., Nakatani H. World Health Organization World health day antimicrobial resistance technical working group. The WHO policy package to combat antimicrobial resistance. Bull World Health Organ. 2011; 89: 390–392. doi: 10.2471/BLT.11.088435.

3. Aslam B., Wang W., Arshad M.I., Khurshid M., Muzammil S., Rasool M.H., Nisar M.A., Alvi R.F., Aslam M.A., Qamar M.U. et al. Antibiotic resistance: a rundown of a global crisis. Infect. Drug Resist. 2018; 11: 1645–1658. doi: 10.2147/IDR.S173867. eCollection 2018.

4. Roope L.S.J., Smith R.D., Pouwels K.B., Buchanan J., Abel L., Eibich P., Butler C.C., Tan P.S., Sarah Walker A., Robotham J.V. et al. The challenge of antimicrobial resistance: What economics can contribute. Science 2019; 364: eaau4679. doi: 10.1126/science.aau4679.

5. Singh M., Dominy B. The evolution of cefotaximase activity in the TEM β-lactamase. J Mol Biol. 2012; 415:205–220. doi: 10.1016/j.jmb.2011.10.041. Epub 2011 Nov 3.

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