Nutrient-wide association study of 57 foods/nutrients and epithelial ovarian cancer in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study

Author:

Merritt Melissa A1ORCID,Tzoulaki Ioanna1,van den Brandt Piet A2,Schouten Leo J2,Tsilidis Konstantinos K13,Weiderpass Elisabete4567,Patel Chirag J8,Tjønneland Anne9,Hansen Louise9,Overvad Kim10,His Mathilde111213,Dartois Laureen111213,Boutron-Ruault Marie-Christine111213,Fortner Renée T14,Kaaks Rudolf14,Aleksandrova Krasimira15,Boeing Heiner15,Trichopoulou Antonia1617,Lagiou Pagona1819,Bamia Christina19,Palli Domenico20,Krogh Vittorio21,Tumino Rosario22,Ricceri Fulvio2324,Mattiello Amalia25,Bueno-de-Mesquita H Bas1262728,Onland-Moret N Charlotte29,Peeters Petra H129,Skeie Guri4,Jareid Mie4,Quirós J Ramón30,Obón-Santacana Mireia31,Sánchez María-José3233,Chamosa Saioa34,Huerta José M3335,Barricarte Aurelio333637,Dias Joana A38,Sonestedt Emily38,Idahl Annika3940,Lundin Eva41,Wareham Nicholas J42,Khaw Kay-Tee43,Travis Ruth C44,Ferrari Pietro45,Riboli Elio1,Gunter Marc J1

Affiliation:

1. Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom

2. Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, Netherlands

3. Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece

4. Department of Community Medicine, Faculty of Health Sciences, University of Tromsø—The Arctic University of Norway, Tromsø, Norway

5. Department of Research, Cancer Registry of Norway, Oslo, Norway

6. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

7. Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland

8. Department of Biomedical Informatics, Harvard Medical School, Boston, MA

9. Danish Cancer Society Research Center, Copenhagen, Denmark

10. Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark

11. Centre for Research in Epidemiology and Population Health, Inserm (Institut National de la Santé et de la Recherche Médicale), Villejuif Cedex, France

12. Univ Paris Sud, Villejuif, France

13. Gustave Roussy, Villejuif, France

14. Division of Cancer Epidemiology, German Cancer Research Center [Deutsches Krebsforschungszentrum (DKFZ)], Heidelberg, Germany

15. Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany

16. Hellenic Health Foundation, Athens, Greece

17. Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece

18. Department of Epidemiology, Harvard School of Public Health, Boston, MA

19. Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece

20. Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute–Istituto per lo Studio e la Prevenzione Oncologica (ISPO), Florence, Italy

21. Epidemiology and Prevention Unit, Fondazione Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milano, Italy

22. Cancer Registry and Histopathology Unit, “Civic–M.P. Arezzo” Hospital, Azienda Sanitaria Provinciale, Ragusa, Italy

23. Unit of Epidemiology, Regional Health Service, Azienda Sanitaria Locale (ASL) TO3, Grugliasco, Italy

24. Unit of Cancer Epidemiology, Department of Medical Sciences, University of Turin, Turin, Italy

25. Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy

26. Department for Determinants of Chronic Diseases, National Institute for Public Health and the Environment [Rijksinstituut voor Volksgezondheid en Milieu (RIVM)], Bilthoven, Netherlands

27. Department of Gastroenterology and Hepatology

28. Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

29. Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands

30. Public Health Directorate, Asturias, Oviedo, Spain

31. Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (Institut Català d’Oncologia (ICO)–Institut d’Investigació Biomèdica de Bellvitge (IDIBELL), Barcelona, Spain

32. Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain

33. CIBER de Epidemiología y Salud Pública, Madrid, Spain

34. Public Health Division of Gipuzkoa, BioDonostia Research Institute, Health Department of Basque Region, San Sebastian, Spain

35. Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain

36. Navarra Public Health Institute, Pamplona, Spain

37. Navarra Institute for Health Research (IdiSNA) Pamplona, Spain

38. Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden

39. Department of Clinical Sciences, Obstetrics and Gynecology

40. Department of Public Health and Clinical Medicine, Nutritional Research

41. Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden

42. Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom

43. Cambridge Institute of Public Health, University of Cambridge, Cambridge, United Kingdom

44. Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom

45. Nutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France

Funder

Swedish Cancer Society

NIH

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference35 articles.

1. World Cancer Research Fund/American Institute for Cancer Research. Food, nutrition, physical activity, and the prevention of cancer: a global perspective [Internet].2007. [cited 2014 Sep 12]. Washington (DC): American Institute for Cancer Research; 2007. Available from: http://www.dietandcancerreport.org/cancer_resource_center/downloads/Second_Expert_Report_full.pdf.

2. Global surveillance of cancer survival 1995–2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2);Allemani;Lancet,2015

3. World Cancer Research Fund/American Institute for Cancer Research. Continuous update project report: food, nutrition, physical activity, and the prevention of ovarian cancer [Internet]. 2014 [cited 2015 Apr 3]. Washington (DC): American Institute for Cancer Research; 2014. Available from: http://www.dietandcancerreport.org/cup/cup_resources.php.

4. Dietary intake and ovarian cancer risk: a systematic review;Crane;Cancer Epidemiol Biomarkers Prev,2014

5. Controlling the false discovery rate: a practical and powerful approach to multiple testing;Benjamini;J R Stat Soc, B,1995

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