Evidence from a Randomized Trial That Exposure to Supplemental Folic Acid at Recommended Levels during Pregnancy Does Not Lead to Increased Unmetabolized Folic Acid Concentrations in Maternal or Cord Blood-Reference-Cited by-同舟云学术

Evidence from a Randomized Trial That Exposure to Supplemental Folic Acid at Recommended Levels during Pregnancy Does Not Lead to Increased Unmetabolized Folic Acid Concentrations in Maternal or Cord Blood

Published:2016-01-27 Issue:3 Volume:146 Page:494-500
ISSN:0022-3166
Container-title:The Journal of Nutrition
language:en
Short-container-title:

Author:

Pentieva Kristina¹^ORCID,Selhub Jacob²,Paul Ligi²,Molloy Anne M³,McNulty Breige⁴,Ward Mary¹^ORCID,Marshall Barry⁵,Dornan James⁶^ORCID,Reilly Rosie¹,Parle-McDermott Anne⁷,Bradbury Ian⁸,Ozaki Mari⁷,Scott John M⁹,McNulty Helene¹

Affiliation:

1. Northern Ireland Centre for Food & Health (NICHE), School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland

2. Vitamin Metabolism and Aging Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA

3. School of Medicine, Trinity College, Dublin, Ireland

4. School of Agriculture & Food Science, University College Dublin, Dublin, Ireland

5. Causeway Hospital, The Northern Health and Social Care Trust, Coleraine, Northern Ireland

6. Royal-Jubilee Maternity Service, Belfast, Northern Ireland

7. School of Biotechnology, Dublin City University, Dublin, Ireland

8. Frontier Science (Scotland), Kincraig, Scotland

9. School of Biochemistry and Immunology, Trinity College, Dublin, Ireland

Funder

Northern Ireland Department for Employment and Learning

Health Research Board

HSC Research and Development

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Link

http://academic.oup.com/jn/article-pdf/146/3/494/23973254/jn223644.pdf

Reference33 articles.

1. Biomarkers of nutrition for development—folate review;Bailey;J Nutr,2015

2. Unmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements;Kelly;Am J Clin Nutr,1997

3. Does folic acid harm people with vitamin B12 deficiency?;Dickinson;QJM,1995

4. Folate-cobalamin interactions;Savage,1995

5. Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors;Morris;Am J Clin Nutr,2010

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5. Detection of maternal serum unmetabolized folic acid following multivitamin and mineral supplementation with or without folic acid after 12 weeks’ gestation: a randomized controlled trial;2022-07-19