1. From the Division of Cardiology, Tokyo Medical University, Tokyo, Japan (CM); the Divisions of Aging (ABP, HDS, JMG, and LD) and Preventive Medicine (HDS and JMG), Brigham and Women’s Hospital, Boston, MA; the Harvard Medical School, Boston, MA (HDS, JMG, and LD); and the Boston Veterans Affairs Healthcare System, Boston, MA (JMG and LD).