Author:
IMRIE R. C.,RAMAIAH T. R.,ANTONI F.,HUTCHISON W. C.
Abstract
SUMMARY
Treatment of female rats with adrenocorticotrophin (ACTH) increased the RNA content of the adrenal glands progressively during a period of 3 days, the DNA content increased only after prolonged administration. By contrast, ACTH caused a decrease in the uptake of [32P]orthophosphate into the total RNA of the gland and into most of the RNA fractions of the subcellular components.
A method of analysis for RNA and DNA based on the Schmidt-Thannhauser procedure has been evolved which eliminates extraction of nucleic acid by lipid solvents.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Cited by
51 articles.
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