Stereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species-Reference-Cited by-同舟云学术

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Stereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species

Published:2021-01-12 Issue:1 Volume:10 Page:23
ISSN:2164-2591
Container-title:Translational Vision Science & Technology
language:en
Short-container-title:Trans. Vis. Sci. Tech.

Author:

Byrne Michael¹,Vathipadiekal Vinod¹,Apponi Luciano¹,Iwamoto Naoki¹,Kandasamy Pachamuthu¹,Longo Kenneth¹,Liu Fangjun¹,Looby Richard¹,Norwood Lauren¹,Shah Anee¹,Shelke Juili Dilip¹,Shivalila Chikdu¹,Yang Hailin¹,Yin Yuan¹,Guo Lankai¹,Bowman Keith¹,Vargeese Chandra¹

Affiliation:

1. Wave Life Sciences, Cambridge, MA, USA

Publisher

Association for Research in Vision and Ophthalmology (ARVO)

Subject

Ophthalmology,Biomedical Engineering

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2. Rational Design of Chimeric Antisense Oligonucleotides on a Mixed PO–PS Backbone for Splice-Switching Applications;Biomolecules;2024-07-22

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4. A highly efficient catalytic method for the synthesis of phosphite diesters;Chemical Science;2024

5. Targeting RNA with synthetic oligonucleotides: Clinical success invites new challenges;Cell Chemical Biology;2024-01

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