Affiliation:
1. Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK
Abstract
Hematopoietic stem and progenitor cells (HSPCs) use specialized adhesive structures referred to as magnupodium to stay in hematopoietic niches. Bessey et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202005085) define new characteristics of the magnupodium, including centriole polarization and the necessary and sufficient role of CXCR4 signaling.
Funder
Kennedy Trust for Rheumatology Research
Publisher
Rockefeller University Press