1. Yale-NUS College, Singapore 138527, Singapore
2. Department of Statistical Sciences, University College, London WC1E 6BT, United Kingdom
3. Yale-NUS College, Singapore 138527, Singapore; Department of Statistical Sciences, University College, London WC1E 6BT, United Kingdom
4. Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College, London SW1 2AZ, United Kingdom