1. Section of Bioinformatics, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London W12 0NN, U.K.
2. Department of Mathematics, Imperial College London, London SW7 2AZ, U.K.
3. National Phenome Centre, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, U.K.