Inhibiting mutant KRAS G12D gene expression using novel peptide nucleic acid‑based antisense: A potential new drug candidate for pancreatic cancer-Reference-Cited by-同舟云学术

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Inhibiting mutant KRAS G12D gene expression using novel peptide nucleic acid‑based antisense: A potential new drug candidate for pancreatic cancer

Published:2022-02-21 Issue:4 Volume:23 Page:
ISSN:1792-1074
Container-title:Oncology Letters
language:
Short-container-title:Oncol Lett

Author:

Shai Ayelet¹,Galouk Evleen¹,Miari Reem¹,Tareef Hala¹,Sammar Marei²,Zeidan Mouhammad³,Rayan Anwar⁴,Falah Mizied¹

Affiliation:

1. Oncology Department, Galilee Medical Center, Nahariya 2210001, Israel

2. Ephraim Katzir Department of Biotechnology Engineering, ORT Braude College, Karmiel 2161002, Israel

3. Molecular Genetics and Virology Laboratory, Al‑Qasemi Center of Research Excellence, Baka EL‑Garbiah 30100, Israel

4. Faculty of Science, Al‑Qasemi Academic College, Baka EL‑Garbiah 30100, Israel

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

Reference55 articles.

1. A comprehensive survey of Ras mutations in cancer;Prior;Cancer Res,2012

2. Ras in cancer and developmental diseases;Fernández-Medarde;Genes Cancer,2011

3. Drugging the undruggable RAS: Mission possible?;Cox;Nat Rev Drug Discov,2014

4. Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: Diagnostic and clinical implications;Tsiatis;J Mol Diagn,2010

5. RAS oncogenes: Weaving a tumorigenic web;Pylayeva-Gupta;Nat Rev Cancer,2011

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3. Peptide Nucleic Acids: Recent Developments in the Synthesis and Backbone Modifications;Bioorganic Chemistry;2023-12

4. Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation;Molecular Cancer;2023-10-09

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