Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

Author:

Chehelgerdi MohammadORCID,Chehelgerdi Matin,Allela Omer Qutaiba B.,Pecho Renzon Daniel Cosme,Jayasankar Narayanan,Rao Devendra Pratap,Thamaraikani Tamilanban,Vasanthan Manimaran,Viktor Patrik,Lakshmaiya Natrayan,Saadh Mohamed J.,Amajd Ayesha,Abo-Zaid Mabrouk A.,Castillo-Acobo Roxana Yolanda,Ismail Ahmed H.,Amin Ali H.,Akhavan-Sigari Reza

Abstract

AbstractThe use of nanotechnology has the potential to revolutionize the detection and treatment of cancer. Developments in protein engineering and materials science have led to the emergence of new nanoscale targeting techniques, which offer renewed hope for cancer patients. While several nanocarriers for medicinal purposes have been approved for human trials, only a few have been authorized for clinical use in targeting cancer cells. In this review, we analyze some of the authorized formulations and discuss the challenges of translating findings from the lab to the clinic. This study highlights the various nanocarriers and compounds that can be used for selective tumor targeting and the inherent difficulties in cancer therapy. Nanotechnology provides a promising platform for improving cancer detection and treatment in the future, but further research is needed to overcome the current limitations in clinical translation. Graphical Abstract

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Molecular Medicine

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