MicroRNA profiling of paediatric AML with FLT-ITD or MLL-rearrangements: Expression signatures and in vitro modulation of miR-221-3p and miR-222-3p with BRD4/HATs inhibitors

Author:

Leoncini Pier1,Vitullo Patrizia1,Reddel Sofia1,Tocco Valeria1,Paganelli Valeria1,Stocchi Francesca1,Mariggiò Elena1,Massa Michele2,Nigita Giovanni3,Veneziano Dario3,Fadda Paolo4,Scarpa Mario5,Pigazzi Martina6,Bertaina Alice1,Rota Rossella1,Pagliara Daria1,Merli Pietro1

Affiliation:

1. Department of Paediatric Haematology and Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, I-00146 Rome, Italy

2. Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, I-00161 Rome, Italy

3. Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210-1239, USA

4. Genomics Shared Resource, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210-1239, USA

5. Department of Biomedical Research, Urology Research laboratory, University of Bern, CH-3008 Bern, Switzerland

6. Department of Women's and Children's Health (SDB), Hematology-Oncology Laboratory, University of Padova, I-35128 Padova, Italy

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,General Medicine

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