Prognostic significance of flow-cytometry evaluation of minimal residual disease in children with acute myeloid leukaemia treated according to the AIEOP-AML 2002/01 study protocol

Author:

Buldini Barbara1,Rizzati Frida1,Masetti Riccardo2,Fagioli Franca3,Menna Giuseppe4,Micalizzi Concetta5,Putti Maria Caterina1,Rizzari Carmelo6,Santoro Nicola7,Zecca Marco8,Disarò Silvia1,Rondelli Roberto2,Merli Pietro9,Pigazzi Martina1,Pession Andrea2,Locatelli Franco9,Basso Giuseppe1

Affiliation:

1. Department of Woman and Child Health; Laboratory of Haematology-Oncology; University of Padova; Padova Italy

2. Department of Pediatrics; Lalla Seragnoli, Haematology-Oncology Unit; University of Bologna; Bologna Italy

3. Pediatric Onco-Haematology; Stem Cell Transplantation and Cellular Therapy Division; Regina Margherita Children's Hospital; Torino Italy

4. Department of Pediatric Haemato-Oncology; Santobono-Pausilipon Hospital; Napoli Italy

5. Department of Pediatric Haemato-Oncology; IRCCS Istituto “Giannina Gaslini”; Genova Italy

6. Department of Pediatrics; Centro Ricerca Tettamanti; Università di Milano-Bicocca; Monza Italy

7. Department of Pediatrics; Policlinico di Bari; Bari Italy

8. Department of Pediatric Haemato-Oncology; Fondazione IRCCS Policlinico S. Matteo; Pavia Italy

9. Department of Pediatric Haematology-Oncology; Istituto di Ricovero e Cura a Carattere Scientifico; Ospedale Bambino Gesù, Rome; University of Pavia; Pavia Italy

Funder

CARIPARO

Istituto di Ricerca Pediatrica-Fondazione Città della Speranza

Università degli Studi di Padova

PRIN 2015

FIRB 2014

TRASCALL

Associazione Italiana per la Ricerca sul Cancro

Publisher

Wiley

Subject

Hematology

Reference54 articles.

1. High frequency of immunophenotype changes in acute myeloid leukemia at relapse: implications for residual disease detection (Cancer and Leukemia Group B Study 8361);Baer;Blood,2001

2. New methodologic approaches for immunophenotyping acute leukemias;Basso;Haematologica,2001

3. Immunophenotyping of acute leukemia by flow cytometric analysis. Use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis;Borowitz;American Journal of Clinical Pathology,1993

4. Determination of minimal residual disease in leukemia patients;Campana;British Journal of Haematology,2003

5. Status of minimal residual disease testing in childhood haematological malignancies;Campana;British Journal of Haematology.,2008

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