Aloe-Emodin Protects RIN-5F (Pancreatic β-cell) Cell from Glucotoxicity via Regulation of Pro-Inflammatory Cytokine and Downregulation of Bax and Caspase 3
Author:
Affiliation:
1. Adipogenesis and Immunobiology Research Lab, Department of Food Sciences and Nutrition, College of Food Sciences and Agriculture, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia
Publisher
The Korean Society of Applied Pharmacology
Subject
Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry
Link
http://ocean.kisti.re.kr/downfile/crosscheck/ksp/JAKO201602152088610.pdf
Reference33 articles.
1. Aloe emodin glycosides stimulates glucose transport and glycogen storage through PI3K dependent mechanism in L6 myotubes and inhibits adipocyte differentiation in 3T3L1 adipocytes
2. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
3. Neogenesis vs. apoptosis as main components of pancreatic β cell mass changes in glucose‐infused normal and mildly diabetic adult rats
4. Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells
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1. Role of anthraquinones in combating insulin resistance;Frontiers in Pharmacology;2023-11-20
2. Aloe-Emodin Derivative, an Anthraquinone Compound, Attenuates Pyroptosis by Targeting NLRP3 Inflammasome in Diabetic Cardiomyopathy;Pharmaceuticals;2023-09-08
3. Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7;Phytomedicine;2023-06
4. Kitul, a food plant with antidiabetic-like effects: Reduction of intracellular reactive species in glucose-stimulated RIN-5F pancreatic β-cells and mitigation of pro-inflammatory mediators in activated RAW 264.7 macrophages;Food Research International;2023-05
5. Molecular targeting of prodigiosin against anti-inflammatory genes cyclooxygenase-1 and -2;Process Biochemistry;2023-03
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