Proposal of Dual Inhibitor Targeting ATPase Domains of Topoisomerase II and Heat Shock Protein 90-Reference-Cited by-同舟云学术

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Proposal of Dual Inhibitor Targeting ATPase Domains of Topoisomerase II and Heat Shock Protein 90

Published:2016-09-01 Issue:5 Volume:24 Page:453-468
ISSN:2005-4483
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomolecules & Therapeutics

Author:

Jun Kyu-Yeon¹,Kwon Youngjoo¹

Affiliation:

1. College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea

Funder

National Research Foundation of Korea(NRF)

Ministry of Health and Welfare(Ministry of Health, Welfare and Family Affairs)

Ministry of Education(Ministry of Education of the Republic of Korea)

Ministry of Science, ICT and Future Planning(MSIP)

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2016/024/bt-24-453.pdf

Reference54 articles.

1. Halohydrin and Oxime Derivatives of Radicicol: Synthesis and Antitumor Activities

2. The topoisomerase II–Hsp90 complex: A new chemotherapeutic target?

3. Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

4. N-Fused Imidazoles As Novel Anticancer Agents That Inhibit Catalytic Activity of Topoisomerase IIα and Induce Apoptosis in G1/S Phase

5. 4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

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1. Small-molecule dual inhibitors targeting heat shock protein 90 for cancer targeted therapy;Bioorganic Chemistry;2023-10

2. Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers;Journal of Advanced Research;2023-05

3. Recent development of multi-targeted inhibitors of human topoisomerase II enzyme as potent cancer therapeutics;International Journal of Biological Macromolecules;2023-01

4. Synthesis and evaluation of 7-(3-aminopropyloxy)-substituted flavone analogue as a topoisomerase IIα catalytic inhibitor and its sensitizing effect to enzalutamide in castration-resistant prostate cancer cells;European Journal of Medicinal Chemistry;2023-01

5. Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy;Molecules;2022-08-29

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