Augmented Pulmonary Vasoconstrictor Reactivity after Chronic Hypoxia Requires Src Kinase and Epidermal Growth Factor Receptor Signaling
Author:
Affiliation:
1. Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico
Publisher
American Thoracic Society
Subject
Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology
Link
https://www.atsjournals.org/doi/pdf/10.1165/rcmb.2018-0106OC
Reference56 articles.
1. Rho Kinase–Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats
2. Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats
3. Inhaled Rho Kinase Inhibitors Are Potent and Selective Vasodilators in Rat Pulmonary Hypertension
4. Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries
5. Chronic hypoxia augments depolarization-induced Ca2+sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA
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