Biased TAS2R Bronchodilators Inhibit Airway Smooth Muscle Growth by Downregulating Phosphorylated Extracellular Signal–regulated Kinase 1/2-Reference-Cited by-同舟云学术

Biased TAS2R Bronchodilators Inhibit Airway Smooth Muscle Growth by Downregulating Phosphorylated Extracellular Signal–regulated Kinase 1/2

Published:2019-05 Issue:5 Volume:60 Page:532-540
ISSN:1044-1549
Container-title:American Journal of Respiratory Cell and Molecular Biology
language:en
Short-container-title:Am J Respir Cell Mol Biol

Author:

Kim Donghwa¹,Cho Soomin²,Castaño Maria A.¹,Panettieri Reynold A.³,Woo Jung A.⁴,Liggett Stephen B.¹⁴

Affiliation:

1. Department of Medicine and

2. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California; and

3. Rutgers Institute for Translational Medicine and Science, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey

4. Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida

Publisher

American Thoracic Society

Subject

Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology

Link

https://www.atsjournals.org/doi/pdf/10.1165/rcmb.2018-0189OC

Reference33 articles.

1. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

2. Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via Gαi1,2,3

3. An Early Response Transcription Factor, Egr-1, Enhances Insulin Resistance in Type 2 Diabetes with Chronic Hyperinsulinism

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