Chronic Obstructive Pulmonary Disease Is Associated with Epigenome-Wide Differential Methylation in BAL Lung Cells

Author:

Eriksson Ström Jonas1ORCID,Kebede Merid Simon2,Pourazar Jamshid1,Blomberg Anders1,Lindberg Anne1ORCID,Ringh Mikael V.34,Hagemann-Jensen Michael5,Ekström Tomas J.46,Behndig Annelie F.1,Melén Erik27

Affiliation:

1. Department of Public Health and Clinical Medicine, Section of Medicine, Umeå University, Umeå, Sweden;

2. Department of Clinical Sciences and Education,

3. Department of Clinical Neuroscience,

4. Center for Molecular Medicine,

5. Department of Cell and Molecular Biology, and

6. Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden; and

7. Sachs Children’s Hospital, Stockholm, Sweden

Funder

King Gustaf V’s and Queen Victoria’s Freemason Foundation

Västerbotten Läns Landsting

Umeå Universitet

Hjärt-Lungfonden

Vetenskapsrådet

Kempestiftelserna

Region Stockholm

Arnerska Research Foundation

Visare Norr Fund/Northern County Councils Regional Federation

Publisher

American Thoracic Society

Subject

Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology

Reference56 articles.

1. Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease

2. Linking COPD epidemiology with pediatric asthma care: Implications for the patient and the physician

3. World Health Organization. Global health estimates 2019: disease burden by cause, age, sex, by country and by region, 2000-2019. Geneva, Switzerland: World Health Organization

4. 2019 [accessed 2021 Jun 3]. Available from: https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates.

5. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

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