Neurological aspects of modern drug addiction

Author:

Litvincev B. S.1,Konstantinov D. P.2,Efimcev A. Yu.3,Petrov A. D.2,Fomichev A. V.4,Sosyukin A. E.1,Malysheva E. V.1,Vorob'eva M. N.4

Affiliation:

1. Institute of Toxicology of the Federal Medical Biological Agency

2. Saint Petersburg City Narcological Hospital

3. Almazov National Medical Research Centre, RF Ministry of Health

4. S.M. Kirov Military Medical Academy, RF Ministry of Defence

Abstract

The article presents the results of neurological examination of 95 patients with drug dependence. Neurological symptoms were evaluated comparatively in patients with non-injecting and injecting forms of dependence (n=17 and n=78, respectively). The obtained data of clinical neurological examination were compared with the indicators of magnetic resonance imaging of the brain and neurophysiological assessment of the state of peripheral nerves. A comprehensive analysis of the results of the study indicated that chronic intoxication with injecting drugs leads to the development of more pronounced and polymorphic neurological symptoms. It is also necessary to take into account the key role of intoxication in the formation of a cascade of reactions that change the functions of the nervous system.

Publisher

Russian Register of Potentially Hazardous Chemical and Biological Substances

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