Abstract
This manuscript delves into the intricate landscape of bladder cancer, highlighting the challenges of early detection and the nuanced considerations involved in chemotherapy decision-making based on patient-specific factors. The Maher Akl's groundbreaking Glucose Mutation Theory, presenting Glucosodiene as a promising breakthrough. The case presentation meticulously details the journey of a 72-year-old woman diagnosed with high-grade papillary urothelial carcinoma, spanning from initial diagnosis to postoperative outcomes. In the face of Bacillus Calmette-Guérin (BCG) therapy failure, Glucosodiene emerges as a safe and reliable alternative, offering a novel and effective treatment avenue, especially in cases where traditional chemotherapy is contraindicated. This approach advocates for Glucosodiene as a primary therapeutic option after the shortcomings of conventional treatments, instilling confidence in its efficacy and safety, particularly for cases deemed ineligible for chemotherapy.
Reference12 articles.
1. Kaseb H, Aeddula NR. Bladder Cancer. [Updated 2022 Oct 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK536923.
2. Saginala K, Barsouk A, Aluru JS, Rawla P, Padala SA, Barsouk A. Epidemiology of Bladder Cancer. Med Sci (Basel). 2020 Mar 13;8(1):15. doi: 10.3390/medsci8010015. PMID: 32183076; PMCID: PMC7151633.
3. Mitra AP, Datar RH, Cote RJ. Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification. J Clin Oncol. 2006 Dec 10;24(35):5552-64. doi: 10.1200/JCO.2006.08.2073. PMID: 17158541.
4. Inamura K. Bladder Cancer: New Insights into Its Molecular Pathology. Cancers (Basel). 2018 Apr 1;10(4):100. doi: 10.3390/cancers10040100. PMID: 29614760; PMCID: PMC5923355.
5. Amjad MT, Chidharla A, Kasi A. Cancer Chemotherapy. [Updated 2023 Feb 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK564367.