[Case Study] Targeting the Warburg Effect with the Glucose Mutation Theory: A Case Study of a 35-Year-Old Female Treated for Stage II Triple-Positive Metastatic Breast Cancer Involving Lymph Nodes Using Glucosodiene Over a 20-Day Period.

Author:

Ahmed AmrORCID,Akl MaherORCID

Abstract

Triple-positive breast cancer, characterized by the overexpression of estrogen receptors (ER+), progesterone receptors (PR+), and human epidermal growth factor receptor 2 (HER2+), poses a formidable challenge in oncology. This subtype, known for its aggressive nature and metastatic potential, requires a comprehensive therapeutic strategy. Current approaches, predominantly involving targeted therapies, face challenges, necessitating the exploration of alternative interventions. The emergence of Glucosodiene, rooted in Maher Akl's theory on glucose mutation, introduces a promising avenue for treatment. This innovative drug demonstrates efficacy in targeting the Warburg effect prevalent in tumors dependent on anaerobic glucose metabolism. A case study involving a 35-year-old woman with stage II triple-positive breast cancer showcases Glucosodiene's impact, revealing a complete absence of active lesions post-treatment. The results indicate its potential as a primary or secondary therapy, complementing traditional treatment protocols. Glucosodiene's mechanism of action positions it as a versatile and impactful option in the realm of cancer therapeutics, offering hope in the pursuit of improved patient outcomes. THE TRIAL IS REGISTERED UNDER CLINICALTRIALS.GOV NUMBER NCT05957939.

Publisher

Qeios Ltd

Reference9 articles.

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4. Addressing the therapeutic landscape, current modalities predominantly focus on targeted therapies, such as anti-HER2 agents like trastuzumab and pertuzumab. These drugs aim to impede HER2-mediated signaling cascades, hindering tumor progression. Despite the remarkable advancements, challenges persist, with treatment limitations and the emergence of resistance posing formidable hurdles.

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