A critical review on human serum Paraoxonase-1 in the literature: truths and misconceptions-Reference-Cited by-同舟云学术

A critical review on human serum Paraoxonase-1 in the literature: truths and misconceptions

Published:2020-06-24 Issue:1 Volume:46 Page:3-8
ISSN:1303-829X
Container-title:Turkish Journal of Biochemistry
language:en
Short-container-title:

Author:

Mackness Michael¹,Sozmen Eser Yildirim²^ORCID

Affiliation:

1. Avenida Princip D’Espanya , Miami Playa , 43892, Tarragona , Spain

2. Ege Universıty Faculty of Medicine, Department of Medical Biochemistry , Bornova Izmir , Turkey

Abstract

Abstract Human serum paraoxonase 1 (PON1) appears to play an important role in the development of a large variety of diseases with an inflammatory component including heart disease, diabetes, rheumatic diseases, neurological diseases and cancer. As such PON1 research is rapidly expanding into new biomedical fields. Unfortunately, this rapid expansion has resulted in a number of problems due to poor experimental design and the spreading of misconceptions in the literature. This review seeks to describe the basic properties of PON1 and the problems and misconceptions that have arisen.

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry, medical,Clinical Biochemistry,Molecular Biology,Biochemistry

Link

https://www.degruyter.com/document/doi/10.1515/tjb-2020-0186/pdf

Reference44 articles.

1. Mackness, M, Mackness, B. Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles. Gene 2015;567:12–21. https://doi.org/10.1016/j.gene.2015.04.088.

2. Précourt, L-P, Amre, D, Denis, M-C, Lavoie, JC, Delvin, E, Seidman, E, et al. The three-gene paraoxonase family: physiologic roles, actions and regulation. Atherosclerosis 2011;214:20–36. https://doi.org/10.1016/j.atherosclerosis.2010.08.076.

3. Costa, LG, Giordano, G, Cole, TB, Marsillach, J, Furlong, CE. Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity. Toxicology 2013;307:115–22. https://doi.org/10.1016/j.tox.2012.07.011.

4. Deakin, S, Leviev, I, Gomaraschi, M, Calabresi, L, Francesshini, G, James, RW. Enzymatically active paraoxonase-1 is located at the external membrane of producing cells and released by a high affinity, saturable, desorption mechanism. J Biol Chem 2002;277:4301–8. https://doi.org/10.1074/jbc.m107440200.

5. Draganov, DI, La Du, BN Pharmacogenetics of paraoxonase: a brief review. Naunyn-Schmiedeberg’s Arch Pharmacol 2004;369:78–88. https://doi.org/10.1007/s00210-003-0833-1.

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Paraoxonase 1 activity in patients with Alzheimer disease: Systematic review and meta-analysis;Chemico-Biological Interactions;2023-09

2. Oksidatif stres paraoksonaz enzim ailesinin (PON) kanser üzerindeki etkisini arttırır mı? Pon ailesinin oksidatif stres ve kanser ilişkisinin incelenmesini amaçlayan bir derleme;Sakarya Medical Journal;2022-11-10

3. Misconceptions about paraoxonase-1;Brazilian Journal of Otorhinolaryngology;2022-01

4. Turkish journal of biochemistry is an open access journal again;Turkish Journal of Biochemistry;2021-02-01