Taraxastane-type triterpene saponins isolated from Pittosporum angustifolium Lodd.-Reference-Cited by-同舟云学术

Taraxastane-type triterpene saponins isolated from Pittosporum angustifolium Lodd.

Published:2015-05-09 Issue:6 Volume:70 Page:403-408
ISSN:1865-7117
Container-title:Zeitschrift für Naturforschung B
language:en
Short-container-title:

Author:

Bäcker Christian¹,Jenett-Siems Kristina²,Siems Karsten³,Niedermeyer Timo H.J.⁴,Wurster Martina¹,Bodtke Anja⁵,Lindequist Ulrike¹

Affiliation:

1. Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst Moritz Arndt University Greifswald, Friedrich-Ludwig-Jahn-Straße 17, 17489 Greifswald, Germany

2. Institute of Pharmacy, Department of Pharmaceutical Biology, Free University of Berlin, Königin-Luise-Str. 2 + 4, 14195 Berlin, Germany

3. AnalytiCon Discovery GmbH, Hermannswerder Haus 17, 14473 Potsdam, Germany

4. Interfaculty Institute of Microbiology and Infection Medicine, Eberhard Karls University Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany

5. Institute of Pharmacy, Department of Pharmaceutical/Medicinal Chemistry, Ernst Moritz Arndt University Greifswald, Friedrich-Ludwig-Jahn-Straße 17, 17489 Greifswald, Germany

Abstract

Abstract Two new taraxastane-type triterpene saponins, named pittangretosides L (1) and C1 (2), were isolated from the leaves of Pittosporum angustifolium Lodd. Their structures were established by NMR spectroscopic, mass spectrometric and chemical means. The in vitro cytotoxicity was evaluated against four cell lines. The compounds exhibited no cytotoxic activity up to a concentration of 130 μm.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/znb-2015-0005/pdf

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