Spurious parathyroid hormone (PTH) elevation caused by macro-PTH
Author:
Affiliation:
1. Laboratory of Clinical Chemistry , 70492 Cliniques Universitaires Saint-Luc, UCLouvain , Brussels , Belgium
2. Endocrinology Department , 70492 Cliniques Universitaires Saint-Luc, UCLouvain , Brussels , Belgium
Publisher
Walter de Gruyter GmbH
Link
https://www.degruyter.com/document/doi/10.1515/cclm-2024-0455/pdf
Reference5 articles.
1. McCarroll, K, Fitzpatrick, D, McCormack, M, Abdelfadil, S, Crowley, V, Lannon, R, et al.. Falsely elevated parathyroid hormone in a patient with osteoporosis: a case report and review. Osteoporos Int 2023;35:737–40. https://doi.org/10.1007/s00198-023-07006-z.
2. Cavalier, E, Carlisi, A, Chapelle, JP, Delanaye, P. False positive PTH results: an easy strategy to test and detect analytical interferences in routine practice. Clin Chim Acta 2008;387:150–2. https://doi.org/10.1016/j.cca.2007.08.019.
3. Prodan, P, Nandoshvili, E, Webster, C, Shakher, J. Asymptomatic elevated PTH level due to immunoassay interference resulting from Macro-PTH: a case report. Endocr Abstr 2016;44CC4. https://doi.org/10.1530/endoabs.44.cc4.
4. Cetani, F, Centoni, R, Marcocci, C. Macro-PTH, a rare cause of unexplained elevated serum PTH levels. J Endocrinol Invest 2023;46:1039–40. https://doi.org/10.1007/s40618-023-02049-9.
5. Wauthier, L, Plebani, M, Favresse, J. Interferences in immunoassays: review and practical algorithm. Clin Chem Lab Med 2022;60:808–20. https://doi.org/10.1515/cclm-2021-1288.
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