Abstract
Abstract
An improved method to obtain naringin, a bitter flavored flavanone glicoside with proven biological activities, from grapefruit (Citrus x paradisi L.) peel waste is described. The proposed modification of the known process, which involves extraction with methanol and crystallization in water with the addition of dichloromethane, requires shorter processing time and reduced solvent volume. Due to the direct method employed, which did not require the 3-day air-drying stage, the hot extraction of fresh grapefruit albedo using methanol led to higher yields of naringin extract in half the time required. To evaluate the obtained naringin which possessed a wide range of pharmacological properties, it was subjected to chemical transformation into the flavone apigenin, an expensive and naturally-occurring flavonoid obtained in low yields.
Subject
Health, Toxicology and Mutagenesis,Industrial and Manufacturing Engineering,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Environmental Chemistry
Cited by
29 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献