Personalized and targeted therapies

Author:

Wiśniewska Magdalena12,Wiśniewski Michał3,Lewandowska Marzena A.456ORCID

Affiliation:

1. Department of Oncology and Brachytherapy , Collegium Medicum Bydgoszcz, Nicolaus Copernicus University , Toruń , Poland

2. Department of Clinical Oncology , Oncology Centre , Bydgoszcz , Poland

3. Outpatient Chemotherapy Department , Oncology Centre , Bydgoszcz , Poland

4. Department of Thoracic Surgery and Tumors , Collegium Medicum Bydgoszcz, Nicolaus Copernicus University , Toruń , Poland

5. Oncology Centre , Bydgoszcz , Poland

6. Department of Molecular Oncology and Genetics , Innovative Medical Forum Oncology Centre , Bydgoszcz , Poland

Abstract

Abstract Biomarker is defined as indicator of normal or pathogenic biological process or response to an intervention or exposure. There are several categories of biomarkers but predictive biomarkers play the most important role in the treatment of neoplasms. In some cancers there may be more than one potential biomarker, and their identification determines the treatment of the patient. Identification of predictive biomarkers allows the development of novel targeted therapies resulting in tailored treatment. In this chapter we discuss most important predictive biomarkers used in contemporary oncology for which there is approved therapies.

Publisher

Walter de Gruyter GmbH

Subject

General Physics and Astronomy,General Materials Science,General Chemistry

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