Author:
Chetrite Gérard S.,Pasqualini Jorge R.
Abstract
Abstract: The human breast contains all the enzymes responsible for local bioformation of estradiol (E: The cells were incubated with physiological concentrations of [: The MCF-7aro cells have a very high aromatase activity because conversion of [: In breast cancer cells, the natural androgens testosterone and androstenedione, have the capacity to control bioformation of estradiol by blocking aromatase activity. The data can provide important information on the control mechanism of estrogen intratumoral levels and open new possibilities in breast cancer treatment.
Subject
Endocrinology,Molecular Biology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
3 articles.
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