Green synthesis of copper nanoparticles from agro-waste garlic husk

Abstract

Abstract The objective of this study was to test the antibacterial activity of copper nanoparticles (Cu NPs) against bacterial pathogens by green synthesizing them from aqueous extracts of garlic husk. The synthesized Cu NPs were examined by UV-visible (UV-VIS) spectroscopy at (200–400 nm), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) analysis, transmission electron microscopy (TEM), and zeta potential analysis. The findings supported the capping, reduction, and production of Cu NPs with an average crystalline size of 14 nm in the husk extract. The minimum inhibitory concentration technique (MIC test) was used to measure the antibacterial activity against Gram-positive (Escherichia coli, Vibrio cholera) and Gram-negative (Bacillus cereus, Staphylococcus aureus) microorganisms. The lowest concentration required for inhibiting the growth of the bacterial strains ranged from 34.7 to 43.04 μg/ml. The above findings suggest that greenly synthesized Cu NPs made from garlic agro-waste may have potential uses in the realm of nanomedicine as an antibacterial drug in the treatment and prevention of bacterial infections due to their superior antibacterial activity.