Perioperative insulin therapy-Reference-Cited by-同舟云学术

Perioperative insulin therapy

Published:2017-10-01 Issue:5 Volume:11 Page:395-404
ISSN:1875-855X
Container-title:Asian Biomedicine
language:en
Short-container-title:

Author:

Leurcharusmee Prangmalee¹,Kositratna Guy²,Tran De Q.³,Schricker Thomas⁴

Affiliation:

1. Department of Anesthesiology , Maharaj Nakorn Chiang Mai Hospital , Chiang Mai University , Chiang Mai 50200 , Thailand

2. Department of Anesthesiology , UF Health , University of Florida College of Medicine , Gainesville , FL 32209 , USA

3. Department of Anesthesia , Montreal General Hospital , McGill University , Montréal , QC H3G 1A4 , Canada

4. Department of Anesthesia , Royal Victoria Hospital , McGill University , Montréal , QC H4A 3J1 , Canada

Abstract

Abstract Surgical patients commonly develop hyperglycemia secondary to the neuroendocrine stress response. Insulin treatment of hyperglycemia is required to overcome the perioperative catabolic state and acute insulin resistance. Besides its metabolic actions on glucose metabolism, insulin also displays nonmetabolic physiological effects. Preoperative glycemic assessment, maintenance of normoglycemia, and avoidance of glucose variability are paramount to optimize surgical outcomes. This review discusses the basic physiology and effects of insulin as well as practical issues pertaining to its management during the perioperative period.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.1515/abm-2018-0014

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