Affiliation:
1. Programa de Pós Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Curso de Farmácia, CCS/UNIVALI, Itajaí, Santa Catarina, Brazil
2. Empresa de Pesquisa Agropecuária e Extensão Rural de Santa Catarina (EPAGRI), 88301-970 Itajaí, Santa Catarina, Brazil
Abstract
Abstract
The triterpenes friedelin (1), β-friedelinol (2) and 3,15-dioxo-21α-hydroxyfriedelane (3) in the aerial parts of Maytenus robusta, a Brazilian medicinal plant with antiulcer potential, were seasonally quantified by gas chromatography flame-ionization detection (GC-FID) using an external standard. The method was found to be linear, precise and sensitive. Compounds 1 and 2 were found in M. robusta leaves and branches, with highest concentrations in the leaves collected in autumn, i.e. 3.21 ± 0.16 and 12.60 ± 1.49 mg g−1 dry weight of 1 and 2, respectively. On the other hand, compound 3 was found only in the branches, with the highest concentrations in winter and autumn (0.21 ± 0.01 and 0.20 ± 0.02 mg g−1). The results allow to define the optimal season and plant parts for the collection of M. robusta as a phytotherapeutic drug.
Subject
General Biochemistry, Genetics and Molecular Biology
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