Metal-free, air-promoted, radical-mediated arylation of benzoquinone with phenylhydrazines

Author:

Sayahi Mohammad Hosein1,Ansari Samira2,Saghanezhad Seyyed Jafar3,Mahdavi Mohammad4

Affiliation:

1. Department of Chemistry , Payame Noor University (PNU), PO Box 19395-3697 , Tehran , I. R. Iran

2. CinnaGen Medical Biotechnology Research Center, Alborz University of Medical Sciences , Karaj , I. R. Iran

3. ACECR – Production Technology Research Institute , Ahvaz , I. R. Iran

4. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences , Tehran , I. R. Iran

Abstract

Abstract An efficient, economic, and air-promoted metal-free method for direct arylation of benzoquinone with phenylhydrazines was developed. This approach leads to the formation of corresponding [1,1′-biphenyl]-2,5-dione derivatives as biological and pharmaceutical materials of interest in good yields, under mild reaction conditions, and at ambient temperature.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

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